Our work advances interdisciplinary social science research on sustainable development, business and human rights, and environmental governance. We explore how international business can become more just and sustainable, engaging with debates on environmental justice, corporate accountability, telecoupling, political ecology, and global supply chain governance. A core focus is on supply chain regulations from the demand side, especially human rights and environmental due diligence (HREDD) laws. We analyze policymaking, institutional design, company compliance, accountability, and the impacts of HREDD in Global South production sites. Methodologically, we blend interviews, participant observation, document analysis, surveys, discourse analysis, transdisciplinary approaches, and network analysis. Geographically, our research centers on Latin America and Europe, complemented by comparative studies elsewhere.